Crystal structure of 5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one
نویسندگان
چکیده
The title compound, C12H9N3O, is an inter-mediate in the synthesis of the muscarinic M2 receptor antagonist AFDX-384. The seven-membered ring adopts a boat conformation and the dihedral angle between the planes of the aromatic rings is 41.51 (9)°. In the crystal, mol-ecules are linked into [001] chains of alternating inversion dimers formed by pairs of N-H⋯O hydrogen bonds and pairs of N-H⋯N hydrogen bonds. In both cases, R 2 (2)(8) loops are generated.
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عنوان ژورنال:
دوره 71 شماره
صفحات -
تاریخ انتشار 2015